NX_B2RUZ4 - SMIM1 - Small integral membrane protein 1 - Function. Regulator of red blood cell formation.

View mouse Smim1 Chr4:154020470-154026085 with: phenotypes, sequences, polymorphisms, proteins, references, function

Decidual cells and the neuronal cells showed weak nuclear immunoreactivity. SMIM1 gene products (22): Antibodies (1), Custom CRISPR Plasmid (1), Proteins (1), SYBR Green Primers (2), , shRNA Products (6), siRNA Products (11) Peer-Reviewed Papers. Related Gene Products. Rabbit Polyclonal Anti-SMIM1 Antibody against Human small integral membrane protein 1 (Vel blood group). Validated for Immunohistochemistry Gene information about ENSG00000235169 / SMIM1 - small integral membrane protein 1 (Vel blood group) Homozygosity for a null allele of SMIM1 defines the Vel-negative blood group phenotype. Jill Storry , Magnus Jöud , Mikael Kronborg Christophersen , Britt Thuresson , Bo Åkerström , Birgitta Nilsson Sojka , Björn Nilsson & Martin L Olsson , 2013 , In : Nature Genetics.

Smim1

Since the genetic background of Vel-negativity was discovered in 2013, DNA-based typing of SMIM1 is responsible for the Vel blood group system (VEL) [MIM i:615264]. The Vel antigen is present on red blood cells from all people except rare Vel-negative individuals who can form antibodies to Vel in response to transfusion or pregnancy. These antibodies may cause severe hemolytic reactions in blood recipients. SMIM1 is a type II transmembrane phosphoprotein and displays the Vel blood group antigen at its carboxyl-terminus. FEBS Lett.

Tested in Western Blot (WB) applications. This antibody reacts with Human, Mouse samples.

18 Mar 2013 from the University of Vermont and France has found the missing molecule—a tiny protein called SMIM1—and the mystery is solved.

RNASE9. SLC6A9. RABL6 .

26 Ene 2017 Se trata de una molécula no descubierta hasta el momento y que nombraron SMIM1. Las personas con esta sangre tienen una mutación en su

Product Number. HPA069088.

Det är därför möjligt att SMIM1 utgör en sedan länge sökt malariareceptor på de röda blodkropparna, säger Jill Storry. Publikation smim1 ID ZDB-GENE-081022-87 Name small integral membrane protein 1 Symbol smim1 Nomenclature History Previous Names. si:dkey-23c22.1; zgc:194254; Type protein_coding_gene Location Chr: 8 Mapping Details/Browsers Description Involved in nucleate erythrocyte development. Välja studier Anmälan och antagning Livet som student Internationella möjligheter Examen och karriär Kompetensutveckling för yrkesverksamma Coronaviruset/covid-19 – information för studenter 2019-05-01 · SMIM1 encodes a 78-amino acid, single transmembrane domain (TMD) containing protein with a predicted TMD at amino acids 47 to 67.
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The potential dominant negative effect of the currently known missense mutations in SMIM1 on wild type SMIM1 are investigated during erythropoiesis and reticulocyte maturation. SMIM1 as an erythroid transmembrane protein, an ideal candidate gene. According to the current human genome annotation, SMIM1 has four exons and encodes a 78-amino-acid protein (calculated weight ~8.7 kDa). SMIM1, the gene underlying Vel, encodes a 78-amino acid erythroid transmembrane protein of unknown function.

HPA069088. Unit … SMIM1 gene products (22): Antibodies (1), Custom CRISPR Plasmid (1), Proteins (1), SYBR Green Primers (2), , shRNA Products (6), siRNA Products (11) Peer-Reviewed Papers. Related Gene Products. SMIM1 - Explore an overview of SMIM1, with a histogram displaying coding mutations, full tabulated details of all associated variants, tissue distribution and any drug resistance data.
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SMIM1, the gene underlying Vel, encodes a 78-amino acid erythroid transmembrane protein of unknown function. The transmembrane orientation of SMIM1 has been debated since experimental data supported both the N- and C-termini being extracellular.

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